Make sure you're sitting down before reading this Symantec KB article which is only 1 month old and clearly states they do _not_ support any current version of their product on ESX if Vmotion is enabled. No, it's not a joke.
It's a _fucking_ joke. Symantec have essentially pulled together a list of random issues that are almost certainly intermittent in nature and could have a near infinite number of causes, and somehow slapped the blame on Vmotion without as much as a single word of how they arrived at this conclusion. When Microsoft shut the AV vendors out of the Vista kernel, I actually felt a little sympathy for them (the AV vendors). But after reading this, I can't imagine the bullshit Microsoft must have had to put up with over the years. It's no wonder Microsoft tried to do their own thing with AV.
I urge every enterprise on the planet who are customers of both VMware and Symantec to rain fire and brimstone upon Symantec (I've already started), because your entire server and VDI infrastructure is at this time officially unsupported. The VMware vendor relationship team have already kicked into gear, we need to raise some serious hell as customers to drive this point home, and hard.
This is absolutely disgraceful and must not stand.
UPDATE The original KB article as been updated, support has been restored to normal!